Autoimmune Lymphoproliferative Syndrome Panel

NY Approved

Test Overview

Clinical Utility

  • Confirmation of the clinical diagnosis.
  • Differentiation from malignant forms of lymphoproliferation.
  • Distinguish sub-type of ALPS.
  • Development of an appropriate treatment plan for affected individuals.
  • Development of an appropriate medical surveillance plan for relatives at risk of lymphoma.

Test Details

Genes

CASP10, CASP8, FASLG, TNFRSF6

Conditions

  • Autoimmune Lymphoproliferative Syndrome (ALPS) Type 1A
  • Autoimmune Lymphoproliferative Syndrome Type IIA (ALPS IIA)
  • Autoimmune Lymphoproliferative Syndrome Type IIB (ALPS IIB)

Lab Method

  • Deletion/Duplication Analysis
  • Next-Gen Sequencing

Ordering Information

Test Code: T990
CPT Codes*: 81479x1
ABN Required: No
Turnaround Time**: 3 weeks
Preferred Specimen: 2-5 mL Blood - Lavender Top Tube
Alternative Specimen: Buccal Swabs

*The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

**Turnaround times are estimates and begin once the sample(s) begin processing at the GeneDx lab and could be extended in situations outside GeneDx’s control.

Resources

Test Documents

Billing

Targeted Variant Testing

FAQs