Amyotrophic Lateral Sclerosis / Frontotemporal Lobar Degeneration Panel

Concurrent analysis of multiple genes associated with amyotrophic lateral sclerosis (ALS) and/or frontotemporal lobar dementia (FTLD). 

NY Approved

Test Overview

Clinical Utility

  • Molecular confirmation of a clinical diagnosis
  • Identification of at-risk family members
  • Assist with treatment/management decisions
  • Recurrence risk assessment

Test Details

Genes

ALS2, ANG, CHCHD10, CHMP2B, FUS, GRN, HNRNPA2B1, MAPT, MATR3, OPTN, PFN1, PRPH, SETX, SLC52A3, SOD1, SPG11, SQSTM1, TAF15, TARDBP, TBK1, TUBA4A, UBQLN2, VAPB, VCP

Conditions

  • Amyotrophic lateral sclerosis (ALS)
  • Dementia
  • Frontotemporal Dementia (FTD)
  • Frontotemporal lobar degeneration (FTLD)
  • Lou Gehrig's disease
  • Motor Neuron Disease

Lab Method

  • Deletion/Duplication Analysis
  • Next-Gen Sequencing

Ordering Information

Important Information

SAMPLES NOT ACCEPTED FROM INDIVIDUALS UNDER 18 YEARS OF AGE.
Test Code: T404
CPT Codes*: 81403x1, 81404x1, 81405x1, 81406x2, 81407x1
ABN Required: No
Turnaround Time**: 4 weeks
Preferred Specimen: 2-5 mL Blood - Lavender Top Tube
Alternative Specimen: Buccal Swabs

*The CPT codes provided are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

**Turnaround times are estimates and begin once the sample(s) begin processing at the GeneDx lab and could be extended in situations outside GeneDx’s control.

Resources

Test Documents

Billing

Targeted Variant Testing

FAQs